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KMID : 0357520070300030205
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Journal of Radiological Science and Technology
2007 Volume.30 No. 3 p.205 ~ p.212
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Usefulness of Pulsatile Flow Aortic Aneurysm Phantoms for Stent-graft Placement
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Kim Tae-Hyung
Song Ho-Young
Ko Gi-Young
Park In-Kook
Shin Ji-Hoon
Lim Jin-Oh
Kim Jin-Hyoung
Choi Eugene K.
Ko Gi-Young
Song Ho-Young
Shin Ji-Hoon
Lim Jin-Oh
Kim Jin-Hyoung
Eugene K. Choi
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Abstract
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To evaluate the feasibility and efficacy of a pulsatile aortic aneurysm phantoms for in-vitro study. The phantoms consisted of a pulsating motor part(heart part) and an aortic aneurysm part, which mimicked true physiologic conditions. The heart part was created from a high-pressured water pump and a pulsatile flow solenoid valve for the simulation of aortic flow. The aortic aneurysm part was manufactured from paper clay, which was placed inside a acrylic plastic square box, where liquid silicone was poured. After the silicone was formed, the clay was removed, and a silicone tube was used to connect the heart and aneurysm part. We measured the change in pressure as related to the opening time(pulse rate, Kruskal-Wallis method) and pressure before and after the stent-graft implantation(n = 5, Wilcoxon’s signed ranks test). The changes in blood pressures according to pulse rate were all statistically significant(p<0.05). The systolic/diastolic pressures at the proximal aorta, the aortic aneurysm, and the distal aorta of the model were , , and , respectively, when the pulse rate was 0.5 beat/second. The pressures changed to , , and , respectively, when the pulse rate was 1.0 beat/second, and , , and , respectively, when it was 1.5 beat/second. When pulse rate was set at 1.0 beat/second, the pressures were , , and after stent-graft implantation. The changes of pressure before and after stent-graft implantation were statistically significant(p<0.05) except the diastolic pressures at the proximal(p =1.00) and distal aorta(p=0.157). The aortic aneurysm phantoms seems to be useful for the evaluation of the efficacy of stent-graft before animal or clinical studies because of its easy reproducibility and ability to display a wide range of pressures.
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KEYWORD
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Experimental investigations, Hemodynamics/Flow dynamics, Aneurysm, Angiography
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